产品编号：T444880
产品规格：5mg
产品价格：面议
| 标准品编号: | T444880 |
| 名称: | Tipifarnib |
| 别名: | 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; (R)-(+)-R 115777; Zarnestra; |
| CAS号: | 192185-72-1 |
| 分子式: | C₂₇H₂₂Cl₂N₄O |
| 外观: | 白色至Pale Beige Solid |
| 熔点: | 211-213°C (dec.) |
| 分子量: | 489.4 |
| 储存: | -20˚C Freezer |
| 溶解度: | Chloroform, Methanol |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000). |
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