产品编号：T292920

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	T292920
名称:	2,3,4,5-Tetrafluoro-α-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-β-oxo-benzenepropanoic Acid Methyl Ester
别名:	(S,Z)-Methyl 3-((1-hydroxypropan-2-yl)amino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate;
CAS号:	1213269-48-7
分子式:	C₁₄H₁₃F₄NO₄
分子量:	335.25
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2,3,4,5-Tetrafluoro-α-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-β-oxo-benzenepropanoic Acid Methyl Ester is used in the synthesis of the drug Levofloxacin (L360000), which is a S-(-) form of Ofloxacin (O245750), an antibiotic used against gram-negative organisms.
参考文献	Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992); Kang, S., et al.: Heterocycles, 45, 137 (1997); North, D.S., et al.: Pharmacotherapy, 18, 915 (1998); Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003);