产品编号：T127788
产品规格：1mg
产品价格：面议
| 标准品编号: | T127788 |
| 名称: | TC KHNS 11 |
| 别名: | 5-[4-[3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl]-6-quinazolinyl]-2-methoxy-3-pyridinecarbonitrile |
| CAS号: | 1431540-99-6 |
| 分子式: | C₂₈H₂₄N₆O₃ |
| 分子量: | 492.53 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | TC KHNS 11 is a potent and selective PI 3-kinase δ inhibitor (biochemical IC50 values are 9, 262, 1650 and 4630 nM for PI 3-Kδ, PI 3-Kα, PI 3-Kβ and PI 3-Kγ, respectively; cellular IC50 values are 49, 3440 and 6530 nM for PI 3-Kδ, PI 3-Kα and PI 3-Kβ, respectively). Selective for PI 3-Kδ over a panel of lipid and protein kinases. Inhibits B-cell function. Exhibits moderate oral bioavailability in vivo. |
| 参考文献 | |
