产品编号：T103500
产品规格：10mg
产品价格：面议
| 标准品编号: | T103500 |
| 名称: | Teprenone |
| 别名: | 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one; Geranylgeranylacetone; Selbex; E 0671; E 36U31; GGA |
| CAS号: | 6809-52-5 |
| 参考CAS号: | 3796-63-2 all trans |
| 分子式: | C₂₃H₃₈O |
| 外观: | Clear Pale Yellow to Light Yellow Oil |
| 熔点: | N/A |
| 分子量: | 330.55 |
| 储存: | Amber Vial, -86˚C Freezer |
| 溶解度: | Chloroform (Slightly), Methanol (Slightly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice. |
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