产品编号：T018560

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	T018560
名称:	Tenofovir Phosphate Diammonia Salt, >90%
别名:	(R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic phosphoric Anhydride, Diammonia Salt; [(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-isohypophosphoric Acid Diammonia Salt;
参考CAS号:	free acid: 206646-04-0
分子式:	C₉H₂₁N₇O₇P₂
外观:	白色至白色固体
熔点:	>56°C (dec.)
分子量:	401.25
储存:	Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
溶解度:	Methanol (Slightly), Water (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Tenofovir Phosphate Diammonia Salt is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
参考文献	Michelson, A.M., et al.: Biochim. Biophys. Acta, 91, 1 (1964); Rosenberg, I., et al.: Collect. Czeck. Chem. Commun., 50, 1507 (1985); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)

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