产品编号：T012000
产品规格：25mg
产品价格：面议
| 标准品编号: | T012000 |
| 名称: | TC ASK 10 |
| 别名: | 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]-,benzamide Dihydrochloride;‡4-tert-Butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide Dihydrochloride; |
| CAS号: | 1005775-56-3 |
| 参考CAS号: | 1005775-55-2 free amine |
| 分子式: | C₂₁H₂₃Cl₂N₅O |
| 外观: | 白色至白色固体 |
| 熔点: | >270° (dec.) |
| 分子量: | 432.35 |
| 储存: | 冰箱, under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | TC ASK 10 is a potent ASK1 inhibitor. It displays selectivity for ASK1 over other kinases including ASK2, MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf. It blocks downstream JNK1/p38 phosphorylation in cells. |
| 参考文献 | |
