产品编号：T010015

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	T010015
名称:	Taxol E
别名:	(αR,βS)-α-Hydroxy-β-[[(2S)-2-methyl-1-oxobutyl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aR-[2aα,4β,4aβ,6β,9α[αR*,βS*(S*)],11α,12α,12aα,12bα]]- α-Hydroxy-β-[(2-methyl-1-oxobutyl)amino]benzenepropanoic Acid 6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aα,4β,4aβ,6β,9α[αR*,βS*(S*)],11α,12α,12aα,12bα]]-‡7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid Deriv.; Paclitaxel Impurity R;
CAS号:	158948-96-0
分子式:	C₄₅H₅₅NO₁₄
分子量:	833.92
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Taxol E is an impurity of Paclitaxel (P132500); an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
参考文献	Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984); Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984); Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995); Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002); Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004)