产品编号：T007310

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	T007310
名称:	TAPI-1 Trifluoroacetic Acid Salt
别名:	N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide Trifluoroacetic Acid Salt;
参考CAS号:	Free Base: 171235-71-5
分子式:	C₂₆H₃₇N₅O₅ • x(C ₂HF₃O₂)
外观:	白色固体
熔点:	>110°C (dec.)
分子量:	499.6011402
储存:	-20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Research Tools; Chiral Molecules; Amino Acids; Enzyme Activators and Inhibitors;
应用:	TAPI-1 Trifluoroacetic Acid Salt is a TNF-α converting enzyme (TACE) inhibitor, which blocks shedding of cytokine receptors. It is a modulation of juxtamembrane cleavage (shedding) of angiotensin-converting enzyme by stalking glycosylation in relation to an alternative shedding protease.
参考文献	Schwager, S.L.U, et al.: Biochemistry, 38, 10388 (1999); Mullberg, J., et al.: J. Immunol., 155, 5198 (1995); Slack, B.E., et al.: Biochem. J., 357, 787 (2001);