产品编号：S820007

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S820007
名称:	Sunitinib N-Oxide-d10
别名:	N-[2-(Diethyloxidoamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide-d10; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethyl-N-oxoaminoethyl)amide-d10;
参考CAS号:	Unlabelled: 356068-99-0
分子式:	C₂₂H₁₇D₁₀FN₄O₃
分子量:	424.53
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Sunitinib N-Oxide-d10, is the labeled analogue Sunitinib N-Oxide (S820005), a derivative of Sunitinib (S820000), which is a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK), used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor.
参考文献	Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

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