产品编号：S790700
产品规格：100mg
产品价格：面议
| 标准品编号: | S790700 |
| 名称: | Sumanirole Maleate |
| 别名: | (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate; (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin- 2(1H)-one (2Z)-2-Butenedioate; |
| CAS号: | 179386-44-8 |
| 参考CAS号: | 179386-43-7 |
| 分子式: | C₁₅H₁₇N₃O₅ |
| 外观: | 白色至Light Beige Solid |
| 熔点: | 200-208°C (dec.) |
| 分子量: | 319.31 |
| 储存: | 冰箱 |
| 溶解度: | DMSO, Methanol |
| 类别: | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines; |
| 应用: | Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000). |
| 参考文献 | |
