产品编号：S688700

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	S688700
名称:	Suberoylanilide Hydroxamic Acid
别名:	N-Hydroxy-N’-phenyloctanediamide; SAHA; Zolinza; Vorinostat;
CAS号:	149647-78-9
分子式:	C₁₄H₂₀N₂O₃
外观:	白色固体
熔点:	161-164°C
分子量:	264.32
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Suberoylanilide Hydroxamic Acid is a potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Suberoylanilide Hydroxamic Acid displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Suberoylanilide Hydroxamic Acid induces differentiation in uman breast cancer cells. Potent Histone deacetylase inhibitor.
参考文献	Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),

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