产品编号:S684490
产品规格:
产品价格:面议
| 标准品编号: | S684490 |
| 名称: | STA 21 |
| 别名: | (±)-3,4-Dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione; 3,4-Dihydro-8-hydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; (±)-Ochromycinone;NSC 628869 |
| CAS号: | 111540-00-2 |
| 分子式: | C₁₉H₁₄O₄ |
| 分子量: | 306.31 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | STA 21 selectively inhibits signal transducers and activators of transcription 3 (Stat3), which is transcription factor that is often found to be constitutively active in human breast cancer (1). It also inhibits osteoclastogenesis in mice and humans (2). In addition, STA 21 has been shown to attenuates the development and progression of inflammation in collagen antibody-induced arthritis and therefore, this compound may be used to develop therapeutic strategies to treat rheumatoid arthritis (3). |
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