产品编号：S143510

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S143510
名称:	Saxagliptin O-β-D-glucuronide
别名:	(2S,3S,5R,6S)-6-(((1R,3S,5R,7S)-3-((S)-1-Amino-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)adamantan-1-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
CAS号:	1155849-58-3
分子式:	C₂₄H₃₃N₃O₈
外观:	白色固体
熔点:	>233°C (dec.)
分子量:	491.53
储存:	Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
溶解度:	Methanol, Water
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Saxagliptin O-β-D-glucuronide, is the derivative of Saxagliptin (S143500), which is a potent dipeptidyl peptidase-4 inhibitor approved for the treatment of type 2 diabetes mellitus.
参考文献	Hong, S., et al.: Drug Metabolism & Disposition, 40, 1345 (2012); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007);