产品编号：S258600
产品规格：250mg
产品价格：面议
| 标准品编号: | S258600 |
| 名称: | SEN 12333 |
| 别名: | N-[4-(3-Pyridinyl)phenyl]-4-morpholinepentanamide; WAY 317538; |
| CAS号: | 874450-44-9 |
| 分子式: | C₂₀H₂₅N₃O₂ |
| 分子量: | 339.43 |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable. |
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