产品编号：S083602

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	S083602
名称:	SAG-d3
别名:	3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide-d3;
参考CAS号:	912545-86-9 unlabelled
分子式:	C₂₈H₂₅D₃ClN₃OS
分子量:	493.08
类别:	Building Blocks; Isotopic Labeled Analogues;
应用:	SAG-d3 is the isotope labelled analog of SAG. SAG is a potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15.
参考文献	DeCamp, D., et al.: J. Biol. Chem., 275, 26322 (2000), Ahn, S., et al.: Nature, 437, 894 (2005), Huangfu, D., et al.: Development, 133, 3 (2006), Loulier, K., et al.: J. Neurochem., 98, 530 (2006),