产品编号：R701690

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	R701690
名称:	(5R)-Rupintrivir
别名:	(2E,4S)-4-[[(2R,5R)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid;
分子式:	C₃₁H₃₉FN₄O₇
外观:	Off-white solid
熔点:	138-140˚C
分子量:	598.66
储存:	-20˚C Freezer, Under Inert Atmosphere
溶解度:	Chloroform, Methanol
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	The 5R-enantiomer of Rupintrivir (R701700). Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease.
参考文献	Arruda, E., et al.: J. Clin. Microbiol., 35, 2864 ( 1997), Dragovich, P., et al.: J. Med. Chem., 42, 1213 (1999), Kaiser, L., et al.: Antivir. Res., 47, 215 (2000), Binford, S., et al.: Antimicrob. Agents Chemother., 49, 619 (2005), Schmidtke, M., et al.: J. Antimicrob. Chemother., 56, 648 (2005), Arden, K., et al.: J. Med. Virol., 78, 1232 (2006),