产品编号：R640043

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	R640043
名称:	R-(-)-Rolipram
别名:	(R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone; (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone; (-)-Rolipram; (R)-Rolipram;
CAS号:	85416-75-7
分子式:	C₁₆H₂₁NO₃
外观:	白色固体
熔点:	132-134°C
分子量:	275.34
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	R-(-)-Rolipram is a phosphodiesterase IV (PDE4) inhibitor and anti-inflammatory agent with some antidepressant activity. It is the R isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor.
参考文献	Semmler, J., et al.: Int. J. Immunopharmacol.: 15, 409 (1993); Sommer, N., et al.: Nat. Med.: 1, 244 (1995); Robichaud, A., et al.: J. Clin. Invest., 110, 1045 (2002); Card, G., et al.: Structure: 12, 2233 (2004);