产品编号：R425062
产品规格：25mg
产品价格：面议
| 标准品编号: | R425062 |
| 名称: | Romidepsin-d8 |
| 别名: | Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl]-d8 Cyclic (35)-Disulfide; [S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4- heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-L-valine (4-1)-Lactone-d8 Cyclic (12)-Disulfide; Antibiotic FR 901228-d8; Chromadax-d8; FK 228-d8; FR 901228-d8; NSC 630176-d8; |
| 参考CAS号: | 128517-07-7-unlabelled |
| 分子式: | C₂₄H₂₈D₈N₄O₆S₂ |
| 分子量: | 548.75 |
| 类别: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
| 应用: | Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor. |
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