产品编号：R318585

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	R318585
名称:	Rhodamine-123
别名:	3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthylium Chloride; 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic Acid Methyl Ester Monohydrochloride; R 22420; R 302; RH 123;
CAS号:	62669-70-9
参考CAS号:	104114-27-4--free base
分子式:	C₂₁H₁₇ClN₂O₃
外观:	Red Solid
分子量:	380.83
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Water (Slightly)
类别:	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Rhodamine-123 is a fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Rhodamine 123 (R123), as a typical of P-glycoprotein substrate, was widely used to quantify P-glycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).
参考文献	Yumoto, R., et al.: J. Pharmacol. Exp. Ther., 289, 149 (1999), Romiti, N., et al.: Toxicol. Appl. Pharmacol., 183, 83 (2002), Mizuno, N., et al.: Pharmacol. Rev., 559, 425 (2003), del Amo, E., et al.: Eur. J. Pharm. Sci., 36, 200 (2009),