产品编号：R143005

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	R143005
名称:	Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide
别名:	4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide
分子式:	C₃₃H₂₂ClF₅N₆O₅
分子量:	713.01
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
参考文献	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)