产品编号：P839643
产品规格：25mg
产品价格：面议
| 标准品编号: | P839643 |
| 名称: | PSI-7977-D5 |
| 别名: | Isopropyl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate-D5; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-1-methylethyl Ester L-Alanine-D5; GS-7977-D5; Sofosbuvir-D5; |
| 参考CAS号: | 1190307-88-0 unlabelled |
| 分子式: | C₂₂H₂₄D₅FN₃O₉P |
| 外观: | 白色至Pale Orange Solid |
| 熔点: | >74°C (dec.) |
| 分子量: | 534.48 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | Chloroform (Slightly), Methanol (Slightly) |
| 类别: | Building Blocks; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | PSI-7977-D5 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| 参考文献 | |
