产品编号：P840110

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	P840110
名称:	Pteroic Acid (>85%)
别名:	4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic Acid; NSC 14972; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid; Methotrexate EP Impurity D N-Desmethyl Impurity
杂质:	Methotrexate EP Impurity D N-Desmethyl Impurity
CAS号:	119-24-4
分子式:	C₁₄H₁₂N₆O₃
外观:	Light Yellow to Brown Solid
熔点:	>300°C (dec.)
分子量:	312.28
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Aqueous Base (Slightly), DMSO (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
参考文献	Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977);

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