产品编号：P839503

产品规格：2mg

产品价格：面议

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产品详情

标准品编号:	P839503
名称:	rel-(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic Acid tert-Butyl Ester
CAS号:	1219086-88-0
分子式:	C₂₇H₃₀N₂O₂F₂Cl₂
分子量:	523.44
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	rel-(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic Acid tert-Butyl Ester is used as a reactant in the synthesis of RG7388, a potent and selective p53-MDM2 inhibitor.
参考文献	Zhao, Yujun, et al.: J. of Med. Chem.,Â58(3),Â1038-1052Â(2015);Ding, Qingjie, et al.: J. of Med. Chem.,Â56(14),Â5979-5983Â(2013)