产品编号：P699102

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P699102
名称:	Pracinostat-d7
别名:	(2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxyacrylamide-d7; (E)-3-[2-Butyl-1-(2-diethylaminoethyl)-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide-d7; Kaempferol 3-O-β-D-(6-E-p-Coumaroylglucoside)-d7; SB 939-d7; SB939-d7; (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide-d7;
CAS号:	1795137-15-3
参考CAS号:	类似: 929016-96-6
分子式:	C₂₀H₂₃D₇N₄O₂
分子量:	365.52
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled Pracinostat. Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies.
参考文献	Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 9, 642 (2010); Razak, A.R.A. et al.: Br. J. Cancer, 104, 756 (2011); Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 10, 1207 (2011);