产品编号：P635000

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P635000
名称:	PLX-4720
别名:	N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide;
CAS号:	918505-84-7
分子式:	C₁₇H₁₄ClF₂N₃O₃S
外观:	白色至白色固体
熔点:	230-233ºC
分子量:	413.83
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly, Heated)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	PLX4720 is a selective inhibitor of mutant B-RAF and its analog, PLX4032, is currently undergoing clinical trials in melanoma. An antitumor agent. Potent B-Raf inhibitor.
参考文献	Conner, S., et al.: J. Biol. Chem., 278, 34548 (2003), Dumaz, N., et al.: Cancer Res., 66, 9483 (2006), Salerno, P., et al.: J. Clin. Endocrinol. Metab., 95, 450 (2010),