产品编号：P580500
产品规格：10mg
产品价格：面议
| 标准品编号: | P580500 |
| 名称: | Plerixafor |
| 别名: | 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane; AMD 3100; JM3100; SID791 |
| CAS号: | 110078-46-1 |
| 参考CAS号: | 8HCl 155148-31-5 |
| 分子式: | C₂₈H₅₄N₈ |
| 外观: | 白色至Pale Beige Solid |
| 熔点: | 123-127°C |
| 分子量: | 502.78 |
| 储存: | Hygroscopic, 冰箱, under inert atmosphere |
| 溶解度: | Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Plerixafor is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). Selective CXCR4 antagonist. |
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