产品编号：P270360
产品规格：25mg
产品价格：面议
| 标准品编号: | P270360 |
| 名称: | N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine 1-Methylethyl Ester |
| 别名: | N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine Isopropyl Ester |
| CAS号: | 1714114-25-6 |
| 参考CAS号: | S,S diastereomer: 1334513-02-8; R,R diastereomer: |
| 分子式: | C₁₈H₁₇F₅NO₅P |
| 分子量: | 453.3 |
| 类别: | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine 1-Methylethyl Ester is an impurity of PSI-7977 (P839640); a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| 参考文献 | |
