产品编号：P219510

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	P219510
名称:	Pemetrexed Diethyl Ester
别名:	Diethyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate
CAS号:	146943-43-3
分子式:	C₂₄H₂₉N₅O₆
外观:	白色至白色固体
熔点:	158 - 163°C
分子量:	483.52
储存:	冰箱
溶解度:	DMSO, Methanol (Slightly)
类别:	Building Blocks; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Pemetrexed Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.
参考文献	Kjell, D.P., et al.: Org. Proc. Res. Development., 9, 738 (2005); Taylor, E. C., et al.: J. Org. Chem., 66, 3726 (2001);