产品编号：P217702

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P217702
名称:	PD-173074-d9
别名:	N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl-d9)urea; PD 173074-d9;
CAS号:	1794979-29-5
参考CAS号:	219580-11-7-unlabelled
分子式:	C₂₈H₃₂D₉N₇O₃
外观:	Yellow Solid
熔点:	83-85°C
分子量:	532.73
储存:	冰箱
溶解度:	Chloroform, Methanol
类别:	Research Tools; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled PD 173074 (P217700). A selective FGFR1 and FGFR3 inhibitor. The compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation.
参考文献	Mohammadi, M., et al.: Science, 276, 955 (1997), Yagasaki, F., et al.: Cancer Res., 61, 8371 (2001), Keats, J., et al.: Blood, 101, 1520 (2003), Buchler, et al.: 9, 119 (2007),