产品编号：P217500

产品规格：2mg

产品价格：面议

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产品详情

标准品编号:	P217500
名称:	PD-166285
别名:	6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one Hydrochloride;
CAS号:	212391-63-4
分子式:	C₂₆H₂₉Cl₄N₅O₂
外观:	Yellow Solid
熔点:	239-242˚C
分子量:	585.35
储存:	Hygroscopic, 冰箱, Under inert atmosphere
溶解度:	DMSO, Methanol
稳定性:	Hygroscopic
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A broad-spectrum receptor tyrosine kinase (RTK) inhibitor which shows anti-angiogenic activity and anti-tumor efficacy in combination with photodynamic therapy (PDT).
参考文献	Star, W., et al.: Cancer Res., 46, 2532 (1986), Sawutz, D., et al.: Biochem. Pharm., 51, 1631 (1996), Voest, E., et al.: Anti-Cancer Drugs, 7, 723 (1996), Connolly, C., et al.: Bioorg. Med. Chem. Lett., 7(18), 2415 (1997), Hamby, J., et al.: J. Med. Chem., 40, 2296(1997),