产品编号：P217450

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P217450
名称:	PD-325901
别名:	N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide; PD 0325901;PD325901
CAS号:	391210-10-9
分子式:	C₁₆H₁₄F₃IN₂O₄
外观:	白色至淡黄色固体
熔点:	112 - 114°C
分子量:	482.19
储存:	-20°C Freezer, Under Inert Atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Research Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	PD-325901 is the mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor; has potent activity in a no. of cancer cell types in vitro. Selective MEK inhibitor‎.
参考文献	Davies, H., et al.: Nature, 417, 949 (2002), Wellbrock, C., et al.: Cancer Res., 64, 2338 (2004), Solit, D., et al.: Cancer Res., 67, 11463 (2007), Adjei, A., et al.: J. Clin. Oncol., 26, 2139 (2008),