产品编号：P122480

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P122480
名称:	P276-00
别名:	2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methyl-3-pyrrolidinyl]-4H-1-benzopyran-4-one Hydrochloride; 2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one Hydrochloride
CAS号:	920113-03-7
分子式:	C₂₁H₂₁Cl₂NO₅
分子量:	438.3
类别:	Research Tools;
应用:	P276-00 is a cyclin-dependent kinase (CDK) inhibitor. P276-00 has shown to be highly selective for cancer cells and has shown to produce potent inhibition of Cdk4-D1 activity. P276-00 also induces apoptosis in human promyelocytic leukemia (HL-60) cells.
参考文献	Joshi, K.S., et. al.: Mol. Cancer Ther., 6, 918 (2007); Mishra, P.B., et. al.: J. Translational Med., 11, 42 (2013)