产品编号：O514500
产品规格：10mg
产品价格：面议
| 标准品编号: | O514500 |
| 名称: | Olaparib |
| 别名: | 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; AZD 2281; KU 0059436; KU 59436; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine; |
| CAS号: | 763113-22-0 |
| 分子式: | C₂₄H₂₃FN₄O₃ |
| 外观: | 白色至白色固体 |
| 熔点: | 207-210°C |
| 分子量: | 434.46 |
| 储存: | 冰箱 |
| 溶解度: | DMSO (Slightly), Methanol (Slightly, Heated) |
| 类别: | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy. Potent PARP inhibitor. |
| 参考文献 | |
