产品编号：N900270
产品规格：10mg
产品价格：面议
| 标准品编号: | N900270 |
| 名称: | NSC 177223 |
| 别名: | 4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; API-1 |
| CAS号: | 36707-00-3 |
| 分子式: | C₁₃H₁₅N₅O₆ |
| 分子量: | 337.29 |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt. |
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