产品编号：N519670

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	N519670
名称:	2-Nitro-1,3-benzenedimethanol
别名:	2-Nitro-m-Xylene-α,α'-diol;
CAS号:	16578-60-2
分子式:	C₈H₉NO₄
外观:	Off 白色至淡黄色固体
熔点:	101-103ºC
分子量:	183.16
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-Nitro-1,3-benzenedimethanol is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
参考文献	Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001); Griffin, D. et al.: J. Am. Chem. Soc., 134, 13103 (2012);