产品编号：N490138

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	N490138
名称:	Nitisinone-d3
别名:	2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione-d3; NTBC-d3; Nitisone-d3; Orfadin-d3; SC 0735-d3;
参考CAS号:	104206-65-7
分子式:	C₁₄H₇D₃F₃NO₅
分子量:	332.25
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites; Pesticides;
应用:	Nitisinone-d3 is the labelled analogue of Nitisinone (N490135), a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.
参考文献	Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),