产品编号：N407768
产品规格：10mg
产品价格：面议
| 标准品编号: | N407768 |
| 名称: | β-Nicotinamide-d4 Mononucleotide (d4-major) |
| 别名: | 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-d4 Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium-d4 Hydroxide, 5'-Phosphate Inner Salt; NMN; Nicotinamide-d4 Mononucleotide; Nicotinamide-d4 Ribonucleoside 5'-Phosphate; Nicotinamide-d4 Ribonucleotide; Nicotinamide-d4 Ribotide; β-D-NMN; β-NMN; |
| 参考CAS号: | 1094-61-7 unlabelled |
| 分子式: | C₁₁H₁₁D₄N₂O₈P |
| 外观: | 白色固体 |
| 熔点: | >113°C (dec.) |
| 分子量: | 338.24 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | Methanol (Slightly), Water (Slightly) |
| 种类: | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Nicotine Derivatives and Metabolites; |
| 应用: | β-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. |
| 参考文献 | |
