产品编号：N182660

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	N182660
名称:	(E)-5-[2-(5-Nitro-2-furyl)vinyl]-2-furoic Acid
CAS号:	18873-34-2
分子式:	C₁₂H₉NO₆
外观:	Yellowish Green Solid
分子量:	263.2
种类:	Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
应用:	(E)-5-[2-(5-Nitro-2-furyl)vinyl]-2-furoic Acid is an intermediate in the synthesis of 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870), which is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870) was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.
参考文献	Taguchi, K., et al.: Endocrinol., 153, 2985 (2012);