产品编号：M763195

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	M763195
名称:	(αR)-2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetate (αS)-α-Methylbenzenemethanamine
CAS号:	76319-53-4
分子式:	C₁₅H₁₃FO₂ • C₈H₁₁N
分子量:	244.2612118
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR)-2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetate (αS)-α-Methylbenzenemethanamine is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
参考文献	Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 ,No pp. given.(2010);