产品编号：M338675

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M338675
名称:	2-​Methyl-​2-​(4-​vinylphenyl)​propanoic Acid
别名:	4-Ethenyl-α,α-dimethylbenzeneacetic Acid;
CAS号:	1256584-72-1
分子式:	C₁₂H₁₄O₂
分子量:	190.24
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-​Methyl-​2-​(4-​vinylphenyl)​propanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Jiang, X. et al.: Eur. J. Med. Chem., 105, 39 (2015); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);