产品编号：M330593

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	M330593
名称:	Methyl 1-Acetyl-2-oxoindoline-6-carboxylate
别名:	1-​Acetyl-​2,​3-​dihydro-​2-​oxo-​1H-​indole-​6-​carboxylic Acid Methyl Ester
CAS号:	676326-36-6
分子式:	C₁₂H₁₁NO₄
分子量:	233.22
种类:	Building Blocks; Miscellaneous;
应用:	Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
参考文献	Arava, V. et al.: Synth. Comm., 47, 975 (2010); Ahluwalia, N. et al.: Am. J. Resp. Crit. Care Med., 190, 867 (2014); Mross, K. et al.: Clin. Cancer Res., 16, 311 (2010); Xu, R., et al.: J. Labelled Comp. Radiopharm., 58, 308 (2015);