产品编号：M323783

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	M323783
名称:	2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol
别名:	2-Methyl-1-[(3-nitroquinolin-4-yl)amino]propan-2-ol; N-(2-Hydroxy-2-methylpropyl)-3-nitroquinolin-4-amine
CAS号:	129655-57-8
分子式:	C₁₃H₁₅N₃O₃
外观:	Yellow Solid
分子量:	261.28
种类:	Standards; Miscellaneous;
应用:	2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
参考文献	Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);