产品编号：M263315

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M263315
名称:	6N-Methoxymethyl Adefovir Dipivoxil
别名:	Adefovir Dipivoxil N6-Methoxymethyl Impurity; 2,2-Dimethylpropanoic Acid [[[2-[6-[(Methoxymethyl)amino]-9H-purin-9-yl]ethoxy]methyl]phosphinylidene]bis(oxymethylene) Ester;
分子式:	C₂₂H₃₆N₅O₉P
分子量:	545.52
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	6N-Methoxymethyl Adefovir Dipivoxil is an impurity of Adefovir Dipivoxil (A280465) which is used as an oral reverse transcriptase inhibitor in the treatment of hepatitis B. 6N-Hydroxymethyl Adefovir Dipivoxil presence indicates the degradation of Adefovir Dipivoxil under specific conditions suggesting the stability of Adefovir Dipivoxil is compromised under such conditions.
参考文献	Yuan, L., et al.: Pharm. Res., 17, 1098 (2000); Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010), Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2010)