产品编号：M199775
产品规格：5mg
产品价格：面议
| 标准品编号: | M199775 |
| 名称: | MCC-950 |
| 别名: | N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide; CP 456773; |
| CAS号: | 210826-40-7 |
| 分子式: | C₂₀H₂₄N₂O₅S |
| 分子量: | 404.48 |
| 种类: | Standards; Molecular Biology; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | MCC950 selectively inhibits pyrin domain-containing protein 3 (NLRP3) inflammasome, a protein complex involved in the inflammatory process (1). The NLRP3 inflammasome is related to a wide range of immune disorders such as multiple sclerosis, inflammatory bowel disease, auto-immune and auto-inflammatory diseases (2). MCC950 has been shown to specifically inhibit the activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes (1). MCC950 is a potential therapeutic for NLRP3-associated syndromes. |
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