产品编号：L378055

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	L378055
名称:	Levothyroxine Glucose Adduct
别名:	3-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)amino)propanoic Acid
分子式:	C₂₁H₂₁I₄NO₉
分子量:	939.01
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Levothyroxine Glucose Adduct is a derivative of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
参考文献	Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997)