产品编号：L329650
产品规格：25μg
产品价格：面议
| 标准品编号: | L329650 |
| 名称: | Leptomycin B |
| 别名: | 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic Acid; Antibiotic CI 940; Antibiotic CL 1957A; CI 940; CL 1957A; Elactocin; Mantuamycin; NSC 364372; PD 114720; |
| CAS号: | 87081-35-4 |
| 分子式: | C₃₃H₄₈O₆ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | >56°C (dec.) |
| 分子量: | 540.73 |
| 储存: | -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Leptomycin B is a Streptomyces metabolite that inhibits nuclear export of the human immunodeficiency virus type 1 regulatory protein Rev at low nanomolar concentrations. It covalently binds to cysteine residue in the center of CRM1/exportin 1 protein. |
| 参考文献 | |
