产品编号：L320102

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	L320102
名称:	Ledipasvir-d6
别名:	N-​[(1S)​-​1-​[[(6S)​-​6-​[5-​[9,​9-​Difluoro-​7-​[2-​[(1R,​3S,​4S)​-​2-​[(2S)​-​2-​[(methoxycarbonyl)​amino]​-​3-​methyl-​1-​oxobutyl]​-​2-​azabicyclo[2.2.1]​hept-​3-​yl]​-​1H-​benzimidazol-​6-​yl]​-​9H-​fluoren-​2-​yl]​-​1H-​imidazol-​2-​yl]​-​5-​azaspiro[2.4]​hept-​5-​yl]​carbonyl]​-​2-​methylpropyl]​-​carbamic Acid Methyl Ester-d6
参考CAS号:	1256388-51-8 unlabelled
分子式:	C₄₉H₄₈D₆F₂N₈O₆
分子量:	895.04
种类:	Building Blocks; Isotopic Labeled Analogues;
应用:	Ledipasvir-d6 is labelled Ledipasvir (L320100) which is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.
参考文献	Lawitz, E., et al.: J. Hepatol., 57, 24 (2012); Afdhal, N., et al.: New England J. Med., 370, 1889 (2014)