产品编号：I824890

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	I824890
名称:	(S)-Isopropyl-2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(4-((4-hydroxyphenyl)thio)phenoxy)phosphoryl)amino)propanoate
分子式:	C₂₇H₃₃N₆O₆PS
分子量:	600.63
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-Isopropyl-2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(4-((4-hydroxyphenyl)thio)phenoxy)phosphoryl)amino)propanoate is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.
参考文献	Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);