产品编号：I821452
产品规格：2.5mg
产品价格：面议
| 标准品编号: | I821452 |
| 名称: | Isoniazid-d4 |
| 别名: | 4-(Pyridine-d4)carboxylic Acid Hydrazide; Isonicotinic Acid-d4 Hydrazide; 4-(Hydrazinocarbonyl)pyridine-d4; 4-(Pyridine-d4)carbonylhydrazine; 4-(Pyridine-d4)carboxylic Hydrazide; 4-(Pyridyl-d4)carbonylhydrazide; 5015 R.P.-d4; Armazid-d4; Armazide-d4; Atcotibine-d4; Isonizide-d4; Isotebezid-d4; Isozide-d4; Robisellin-d4; Sauterazid-d4; Zinadon-d4; Zonazide-d4; Tubazid-d4; |
| CAS号: | 774596-24-6 |
| 参考CAS号: | 54-85-3 unlabelled |
| 分子式: | C₆H₃D₄N₃O |
| 外观: | 白色至Pale Beige Solid |
| 熔点: | 159 - 161°C |
| 分子量: | 141.16 |
| 储存: | 冰箱 |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
| 应用: | Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic). |
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