产品编号：I820850

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	I820850
名称:	Isoliquiritigenin
别名:	(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; 2',4,4'-Trihydroxychalcone; GU 17;
CAS号:	961-29-5
分子式:	C₁₅H₁₂O₄
外观:	Yellow Solid
熔点:	>193°C (dec.)
分子量:	256.25
储存:	冰箱
溶解度:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. ISL induces quinone reductase-1, a phase II enzyme that deactivates radicals and electrophiles, with a concentration required to double activity (CD) value of 1.8 μM in murine hepatoma cells.
参考文献	Agrawal, R., et al.: Food Chem. Toxicol., 36, 975 (1998), Baba, M., et al.: Biol. Pharm. Bull., 25, 247 (2002), Chowdhury, S., et al.: Anticancer Res., 25, 2055 (2005),